The Venom series of figures were a spin-off of the Spider-Man toyline And featured no Spider-Men at all. They both seem to be aimed more at collectors than anyone else and feature figures of characters that only appeared in the comics.
This Spider-Man spin-off series of figures was aimed more at collectors and feature characters from the Venom mini-series of the same name. The figures are mostly to the larger 6 inch scale, with the exception Scream who is a bit shorter than the average 6 inch figure but still taller than the standard 5 inch figures from the Spider-Man lines.
The gimmick in this line is that each figure has an action feature relating to that character. Each figure came with a symbiote slime pod and most figures have at least one variant.